Your financial institution is undergoing a major upgrade of its sanctions screening program to adapt to a more complex global regulatory environment and support business expansion. As a member of the Compliance department, you've been tasked with designing a comprehensive framework for this new program. Walk me through your approach to building this out. What are the key considerations, technology choices, and staffing requirements? What potential challenges might arise during implementation, and how would you address them?

你的金融机构决定全面升级其制裁筛查项目，以应对日益复杂的国际监管环境和业务扩张需求。作为合规部的一员，你被要求设计一个全面的制裁筛查项目框架。请详细阐述你会如何着手构建这个项目，包括需要考虑的关键要素、技术选择、人员配备以及项目实施过程中的潜在挑战和应对策略。